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H2 blockers can lower vitamin B12 concentrations in the body by impairing how pepsin in the body works, which is necessary for efficient B12 absorption

New Insights on Muscle Strength: The Role of Inhibiting an Enzyme that Hinders NAD+ Synthesis University of Texas Medical Branch researchers show that treating with an inhibitor of an enzyme that breaks down an NAD+ precursor enhances muscle strength and endurance and shortens recovery time in aged mice

It is often used when there is a need for quick replenishment of Vitamin B12 levels, especially in individuals who have difficulty absorbing this nutrient through their diet or oral supplements

For a quick summary of common shot side effects see this guide: B12 shot side effects