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Abstract Semaglutide is often optimized to maximize weight loss, yet it remains unclear whether long-term cardiovascular benefit is more closely associated with achieved weight reduction or therapeutic exposure

When used as part of a medical weight loss program alongside a calorie-deficient diet and regular exercise, Wegovy has proven to be incredibly beneficial in providing effective and long-lasting weight loss results

Eli Lilly has submitted it for approval in more than 40 countries, the UK among them, but no MHRA timeline has been confirmed

Ozempic is not FDA approved for weight management