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PARP inhibitors have also been studied in adjuvant settings

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In pancreatic cells, -arrestin-1 scaffolds ERK1/2, producing a delayed cytosolic phase with anti-apoptotic effects, while shaping GLP-1R trafficking (internalization and recycling) and the compartmentalization of cAMP, including sustained endosomal cAMP generation

Rising azole-resistant Aspergillus fumigatus underscores the need for novel agents, including ibrexafungerp, fosmanogepix, and olorofim, now in clinical trials