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However, some fish studies also reported that dietary l-carnitine could increase the muscle carnitine content in African catfish and zebrafish ( Reference Li, Li and Qin 27 , Reference Ozrio, Uktoseja and Huisman 50 , Reference Ozrio, Van Ginneken and Van den Thillart 51 )

All three of these medications are part of a new generation of metabolic therapies originally developed for diabetes and obesity

However, in patients with established atherosclerotic cardiovascular disease, high cardiovascular risk, or chronic kidney disease, they are now recommended as first-line therapy [22]

So the right balance, especially with other nutrients like selenium, is critical