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The method of any one of embodiments 1-10, wherein the therapeutic agent is a JNK inhibitor
Depending on their subtype, TAMs can produce either pro-inflammatory cytokines (e.g., IL-1 and IL-6) or anti-inflammatory cytokines (e.g., IL-4 and IL-10), thereby modulating the cytokine profile and shifting the tumor microenvironment toward either tumor suppression or tumor promotion (91)
R., Wong, C., Hackam, D
This supports a growing body of evidence that LTF can modulate cellular damage and death induced by acute inflammation
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