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In septic mice, semaglutide attenuated sickness behavior, hypothermia, systemic inflammation, and lung injury through the downregulation of pro-inflammatory cytokines (TNF- , IL-1, IL-6, CXCL1), suppression of neutrophil infiltration, and decreased expression of genes associated with tissue remodeling and inflammation (Mmp9, Timp1, Ly6g)

Van DerSchootA, Drysdale C, Whelan K,DimidiE. The effect offibersupplementation on chronic constipation in adults: An updated systematic review and meta-analysis of randomized controlled trials.AmJ ClinNutr.2022;116:953-969. doi:10.1093/ajcn/nqac184