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2011 Apr 1;589(Pt 7):1509-10

In skin, for instance, some peptides upregulate collagen and downregulate matrix breakdown, leading to a 20 to 30 percent reduction in wrinkle depth after a month of regular topical application in a few studies

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Clinical Evidence Comparison Cerebrolysin: Extensive Clinical Research Base Cerebrolysin has one of the most extensive clinical research bases of any neurotrophic agent, spanning more than three decades of human studies: Alzheimer's Disease Meta-Analysis: Gauthier et al