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Common side effects include: Nausea (most common, usually improves over time) Vomiting or diarrhea Constipation Rarely, pancreatitis or gallbladder issues For a deeper dive into risks and what to watch for, see our dedicated guide: GLP-1 Side Effects Explained by Doctors

In an interim analysis of clinical trials, patients were assigned to receive resmetirom (80 mg or 100 mg) or a placebo

[1] [2] Tirzepatide (Mounjaro, Zepbound) is a dual GIP/GLP-1 receptor agonist with similar clinical effects

A structured meal should include: Protein in every meal Balanced fiber intake Controlled carbohydrate portions Regular meal timing Many patients lose weight rapidly during treatment, but muscle preservation becomes critical for maintaining metabolism afterward

Its reasoning is that these set realistic efficacy expectations and surface contraindications or drug interactions before anything is prescribed