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[3] Although cigarettes had been regarded as a physical and moral hazard by early anti-tobacco movements, by the end of World War I, popular support for distributing cigarettes to troops increased

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When consumed together, this mixture creates enhanced, synergistic effect often referred to as the "entourage effect"

The women who did not add folic acid to their diet during pregnancy (N=16) stopped smoking in 5 cases (31.3%) while 11 (68.7%) continued the habit