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51, 77 The role of these ions in the regulation of the normal intestinal physiology and pathobiology including mucosal inflammation is well recognized

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doi: 10.1038/ncomms6418 191 XiaoYLiangLHuangMQiuQZengSShiMet al

One strategy to consider when starting creatine is called loading. The basic principle behind loading is taking a higher dose of creatine and splitting it throughout the day, then repeating the same practice for several days before returning to a regular dose