Patients with type 2 diabetes and obesitythe primary populations receiving tirzepatidehave multiple independent risk factors for acute pancreatitis that exist regardless of medication use
-glutamyl kinase (GK) encoded by PRO1 in eukaryotes or proB in prokaryotes, the first enzyme in proline biosynthetic pathway, catalyzes the formation of intermediate -glutamyl phosphate, which if accumulated could partially react with cysteine to generate -GC, and then Gsh2 adds glycine to -GC to form GSH
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Spinach is easy to add to salads, smoothies, or cooked dishes
Management: Stay hydrated with electrolyte-containing fluids