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Consult your doctor before use if pregnant, nursing, have a medical condition or take medication

Proc Natl Acad Sci U S A 105:1356813573 Shibata T, Kokubu A, Saito S, Narisawa-Saito M, Sasaki H, Aoyagi K, Yoshimatsu Y, Tachimori Y, Kushima R, Kiyono T, Yamamoto M (2011) NRF2 mutation confers malignant potential and resistance to chemoradiation therapy in advanced esophageal squamous cancer

NTS1 has also been implicated in sleep and psychiatric disorders which often co-occur with AUD and can increase the proclivity for relapse

So, drugs that lead to substantial weight loss could be associated with a decrease in incidence of these obesity-related cancers