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4E), indicating that the clientizing mutation weakens transient contacts between the N- and C-terminal halves

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Results One-week treatment of DIO mice with G49 rapidly increases lipolysis and induces a beiging immune signature in visceral WAT In our previous study, we reported the efficacy of G49 (100 nmol/kg) in DIO mice treated for 3 weeks in reducing steatosis and hepatic inflammation in parallel with a reduction in body weight and improvement in liver regeneration 13

He et al., 2016)