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While his biochemist parents worked, Sinclair spent most of his childhood with his fun-loving, free-spirited grandmother, who admonished him to never grow up

This not only enhances accumulation at the disease site but also potentially improves cellular uptake and efficacy while minimizing off-target effects and systemic exposure to high doses (151)

Endometriosis-associated infertility: aspects of pathophysiological mechanisms and treatment options