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10.1016/j.jep.2021.114759 70 YangT.QuX.WangX.XuD.ShengM.LinY.et al (2024)

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SAM acts as a key methyl donor for most methylation modifications, including the methylation of DNA, RNA, lipids and histones, and also participates in polyamine biosynthesis, which has a function in multiple cellular processes including regulation of chromatin structure, transcription and translation, DNA stabilization, cell growth and proliferation [50]

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For many of these people, they have been told that surgery is the only option because an MRI showed stenosis