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Surprisingly, a slight improvement in change of peak oxygen consumption (peak VO 2 ) was observed in the albiglutide group compared with placebo (mean 0.9 0.5 ml/kg/min versus 0.6 0.5 ml/kg/min

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However, the consistent prevalence of side effects across studies highlights the importance of patient education, tailored dosing regimens, and close monitoring to mitigate these issues