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Lancet 397(10291):22842303 Bonfili L, Cecarini V, Cuccioloni M, Angeletti M, Berardi S, Scarpona S, Rossi G, Eleuteri AM (2018) SLAB51 probiotic formulation activates SIRT1 pathway promoting antioxidant and neuroprotective effects in an AD mouse model

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AMPK ACTIVATION AND ENERGY SENSOR SIGNALING NAD+ accumulation activates not only SIRT1 but also AMPK (AMP-activated protein kinase) through NAD+-dependent regulatory mechanisms