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If fatigue persists, our clinical team is always available to adjust your plan and ensure you are being properly nourished

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When initiating RYBELSUS , consider reducing the dose of concomitantly administered insulin secretagogue (such as sulfonylureas) or insulin to reduce the risk of hypoglycemia RYBELSUS delays gastric emptying and has the potential to impact the absorption of other oral medications

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The percent mediated was calculated as the (total effect direct effect) / total effect 100%, and the standard error (and, hence, the 95% CI) of the percent mediated was estimated using the delta method