Higher concentrations (0.1% or above) risk copper overload on compromised skin, which can trigger the copper uglies: persistent redness, breakouts, and worsening sensitivity
Studies also supported that some toxic metal ions including antimony, arsenic, chromium, cobalt, nickel, and vanadium were responsible to develop high concentrations of ROS during redox reactions in eukaryotic cells
Tamoxifen induced expression of p53 and p21(waf1/cip1), and stimulated G0-G1 phase cell cycle arrest [82]
Also, La-carnitine acts as a carrier for translocating long chain fatty acids across the inner mitochondrial membrane for -oxidation in Krebs cycle and ATP production for sperm motility (78, 79)
The compounds dual action on recovery and sleep quality makes it a frequently selected option for recovery-focused protocols