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Notably, Pa DHDPR showed no inhibition at concentrations up to 0.2 mM ASA, which was consistent with results for Ec DHDPR and Mt DHDPR 23,26

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Interestingly, autoreactive IgG1 is found in serum early in the clinical development of pemphigus foliaceus, and a subclass switch to IgG4 has been postulated to be an important pathological driver [169]

389 The interaction between GLP-1 and its receptor GLP-1R initiates the AMPK signaling cascade within skeletal muscle tissue