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A notable example is the downregulation of GLUT1 glucose transporters, leading to glucose hypometabolismone of the defining features of AD-related astrocyte dysfunction 75

Nigella sativa and Its Active Compound Thymoquinone in the Clinical Management of Diabetes: A Systematic Review by Mahomoodally et al

So if people feel more energetic on GLP-1, its usually an indirect effect , not a direct one

Many triggering agents can cause the disease to become active

5.2 Mitochondrial dysfunction Mitochondrial dysfunction plays a pivotal role in the pathogenesis of HTN-related OS, acting as both a major source and a vulnerable target of ROS in the cardiovascular system