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However, clinicians should remain vigilant for signs of excessive metabolic suppression or thyroid dysfunction, particularly in patients with pre-existing thyroid conditions or those experiencing symptoms beyond cold intolerance, such as severe fatigue, hair loss, or cognitive changes that might suggest thyroid hormone imbalance requiring investigation

10.2337/db14-1577 72 ZhaiR.XuH.HuF.WuJ.KongX.SunX

Lovshin, J., Estall, J., Yusta, B., Brown, T

Besides this, the combined therapy of l-carnitine and metformin further significantly decreased the time spent at the periphery of the open field as compared to the untreated diabetic rats and metformin-alone-treated diabetic rats

When this reverse cholesterol transport functions properly, circulating cholesterol levels are reduced