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The cycle is completed when the keto intermediate is cleaved between C2 and C3 by thiolysis by a 3-ketoacyl-CoA thiolase with acetyl-CoA and the CoA ester of a fatty acid two carbons shorter than the original as the products

A phase II pharmacokinetic study by Jett et al

Green tea has been part of traditional diets for centuries and is now one of the most extensively researched plant-based ingredients in dietary supplements

Copper supplementation in both animal models and humans (e.g., patients with SCO2 mutations) can restore CCO activity, reverse hypertrophy and fibrosis, and significantly improve cardiac function [51, 52]

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