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Additionally, it promotes collagen production, contributing to firmer skin

The peptide enhances sleep quality, particularly slow-wave (deep) sleep phases when natural growth hormone secretion normally peaks

It also suppressed TGF- activation and inflammatory cytokines, thereby resulting in the breakdown of the ECM accumulation pathway [58]

doi:10.1371/journal.pone.0033944 Lederman RJ, Mendelsohn FO, Anderson RD, Saucedo JF, Tenaglia AN, Hermiller JB, Hillegass WB, Rocha-Singh K, Moon TE, Whitehouse MJ et al (2002) Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): a randomised trial

Tesamorelin works upstream by improving growth hormone signaling