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I think whats really missing are larger-scale clinical studies. Previous small studies have shown promise about the drugs in pets, enough for some veterinarians to prescribe human GLP-1 drugs off label to cats, per the outlet

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INTRODUCTION TO INSULIN-LIKE GROWTH FACTOR (IGF-1) Insulin-like growth factor (IGF-1) is a protein hormone produced mainly in the liver that plays a key role in cell growth and development