Animal data show enhanced metabolic adaptation when MOTS-c is dosed before exercise
In addition, lactulose converts freely diffusible ammonia into non-absorbable ammonium ions, thereby reducing intestinal ammonia absorption, while its cathartic effect enhances fecal nitrogen excretion and lowers systemic ammonia levels [122]

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In accordance with our kinetic data (Table 2), it can be assumed that Thr at this position is associated with increased catalytic activity