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Osteocyte dysfunction remains a key contributor to abnormal bone remodeling in advanced disease (Zhu et al., 2020

The math also favors multiple cycles

| | 5-Amino-1MQ Monotherapy | None | 50100mg daily | Daily oral or subcutaneous | NNMT inhibition preserves NAD+, activates AMPK and mitochondrial fat oxidation | 812 weeks | Promising preclinical data

For a complete approach, pair your supplement with a targeted depigmentation serum to address pigmentation from both the inside and outside

It also stimulates melanogenesis by activating MC1 receptors in melanocytes, leading to increased skin pigmentation without UV exposure