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Pinch a fold of skin at the injection site using your thumb and fingers, then insert the needle at a 90-degree angle into the pinched skin

The 600% increase in GLP-1 usage from 2019 to 2024 reflects both the medications' effectiveness and the urgent need for obesity treatments ^18

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Black and tarry stools may also occur due to: Abnormal blood vessels in the esophagus, stomach, or duodenum A tear in the esophagus from violent vomiting (Mallory-Weiss tear) Blood supply being cut off to part of the intestines Inflammation of the stomach lining (gastritis) Trauma or foreign body Widened, overgrown veins (called varices) in the esophagus and stomach, commonly caused by liver cirrhosis Cancer of the esophagus, stomach, duodenum, or ampulla of Vater When to Contact a Medical Professional Contact your health care provider right away if: You notice blood or changes in the color of your stool You vomit blood You feel dizzy or lightheaded In children, a small amount of blood in the stool is most often not serious