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Mechanistically, it activates Nrf2 and its nuclear translocation, thereby enhancing the expression of downstream antioxidant genes to relieve oxidative stress

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WADA 2026 Prohibited List Status (Section S2) Ipamorelin is named on the World Anti-Doping Agency 2025 and 2026 Prohibited Lists under section S2.2.4 (Growth Hormone Releasing Factors) as an example growth hormone secretagogue