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An engineered G q was designed based on the mini-G s scaffold with its N-terminus replaced by corresponding sequences of G i1 to facilitate the binding of scFv16 (Supplementary Fig

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On top of this, OPCs were shown to form direct contacts with neuronal synapses, to participate in synaptic engulfment, and to engage in axon pruning during development and adulthood, thus contributing to circuit formation and modulation in mice (Bergles et al., 2000

Always consult a qualified medical professional before commencing any therapy