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The energy and cognitive benefits are well-reported anecdotally and in smaller human trials, with larger trials currently underway

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Although considerably smaller than the 34000Da peptide drugs, these small molecules are still around 700Da molecular weight further adding to computational modelling complexity

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Taken together, the evidence suggests that class-wide disease modification in Parkinsons, at the compounds and doses tested so far, is unlikely, even if a responder subgroup may yet exist