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Journal of Clinical Psychopharmacology
Semaglutide, on the other hand, works more directly by reducing appetite and helping people feel full longer
17 In addition to these findings, the SUSTAIN-6 trial also showed that semaglutide can offer a significant reduction in the risk of new or worsening nephropathy including persistent macroalbuminuria, increase in serum creatinine or the need of renal replacement therapy
In some studies, people who take semaglutide experience up to 15% weight loss in 68 weeks
Specifically, semaglutide 2.0 mg reduced HbA1c by 0.44% points more than dulaglutide 3.0 mg and by 0.28% points more than dulaglutide 4.5 mg [9]
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