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doi: 10.1056/NEJMoa2008250 28 TeitsmaXMMarijnissenAKBijlsmaJWLafeberFPJacobsJW

Cerebral ischemia not only triggers local neuroinflammation and neuronal damage, but also, via autonomic nervous imbalance, reduced intestinal perfusion, and elevated systemic inflammatory mediators, compromises gut barrier function and disrupts the composition of the gut microbiota (170, 171)

Stomach Upset or Bloating Oral glutathione may cause mild gastrointestinal issues in some individuals, including bloating or stomach discomfort, especially if taken on an empty stomach

The circulating levels of IGF1 change markedly with age, peaking at puberty, and slowly declining with increasing age