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Citrulline and urinary orotic acids are increased

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134,135,136,137 UBE2K attaches ubiquitin to the Lys48 position of Lys63-linked polyubiquitin chains to form branched polyubiquitin chains, which potentially serve as more efficient signals to transport substrates to the 26S proteasome

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In addition, neuropeptides such as NPY, orexin, and 5-HT modulate MTN membrane potential, firing frequency, and I h and Na + currents, thereby playing important roles in rhythmic mastication and oromotor control (Tanaka et al., 2019