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Comment: Many commenters did not support the proposed change to maintain voluntary reporting for the Excessive Radiation eCQM, noting that while CT scans provide essential, life-saving diagnostic benefits, they are frequently performed using radiation doses that are higher than necessary for accurate diagnosis

Current state (February 2026) HRV: 36ms (was 60ms at peak = -40%, but up from 24ms nadir) Min HR: 60.5 bpm (was 52.8 bpm = +15%) Deep Sleep: 70 min (was 116 min = -40%) The most important finding: Comparing identical doses before and after shows the washout made a lasting difference: The same 5mg dose produces 29% better HRV after the washout

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The company has been testing two of its therapies in combination with Novo Nordisks semaglutide