For best results, place on the inner cheek or under the tongue
however, if SGLT2is are not tolerated or are contraindicated, or if eGFR is less than adequate, a GLP-1RA with proven CV benefit can be added (18)
In severe cases hypoglycemia can cause confusion, excess sweating, disturbed sleep, seizures and loss of consciousness
Analytical studies usually include peptide mapping, impurity profiling, degradation analysis, structural characterization, stability testing, and comparative studies with the reference listed drug
However, bringing prescription medications across the border without valid Canadian prescriptions carries legal risks and is generally not advisable