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doi: 10.1038/s42255-022-00531-x 21 JacobsenLMDigginsKBlanchfieldLMcNicholsJPerryDJBrantJet al

Once prepared, PRP is injected into and around the plaque to: Promote collagen remodeling Support improved blood flow Encourage healthier tissue regeneration This combined approach leverages both mechanical stimulation and biologic signaling , aiming to soften plaque and improve penile flexibility over time

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Similarly, in aged rodents, both intranasal and intramuscular administration of Epitalon led to elevated IL-2 expression specifically in certain hypothalamic nuclei [49]