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To further verify whether OGD treatment could cause endothelial cell senescence, -galactosidase (SA--gal) staining was performed on the endothelial cells treated with OGD

Typical dosing: Weekly, gradually titrated Common side effects: Nausea, reflux, constipation, diarrhea, reduced appetite Important note: Coverage and cost vary

Vitamin B12 Injections Vitamin B12 injections are used in some cases to help restore vitamin B12 levels

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Nrf2 functions to inhibit NF-B activation and decrease the production of inflammatory factors, thereby impeding the progression of arthritis [110]