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By integrating two hormonal mechanisms of action, the treatment aims to influence both appetite regulation and glucose metabolism more comprehensively than treatment with a single substance.

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They notably increase mean GH levels and IGF-1 levels after prolonged use

Voxel-based morphometry (VBM) analysis demonstrated that liraglutide-treated participants showed a slower reduction in whole cortical grey matter, frontal, temporal and parietal lobe volume in participants treated with liraglutide compared to placebo