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Diagnosis: How Carnitine Deficiency is Confirmed Diagnosing carnitine deficiency in dogs involves a combination of clinical assessment and specific testing: Blood carnitine levels: Plasma and whole-blood carnitine measurement is the most direct way to identify deficiency

The AAFPs evidence-based clinical review states directly: Oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms in patients with B12 deficiency (Langan RC, Goodbred AJ, American Family Physician, 2017)

They both require pyridoxal-5-phosphate, the active form of vitamin B6, as a cofactor for their enzymatic activity [26, 27, 28]

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doi: 10.1111/andr.13029