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Efficacy and safety of semaglutide combined with metformin in treating T2DM with overweight or obesity: a systematic review and meta-analysis

doi:10.1016/j.phrs.2023.106814 Mielgo-Ayuso J, Pietrantonio L, Viribay A, Calleja-Gonzlez J, Gonzlez-Bernal J, Fernndez-Lzaro D

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Because those peptides arent components of an approved drug and dont carry a USP monograph, compounders werent allowed to dispense them anyway

Previous studies have identified the gut microbiota as a key component in the regulation of GLP-1 secretion, although the mechanisms of action and organisms responsible for this activity have not been well-defined 20