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A 2020 preclinical toxicity review found no serious toxicity in mice, rats, rabbits, or dogs at tested doses, but longterm human carcinogenicity or organtoxicity data are missing

High-dose folic acid supplements showed improvement in sperm parameters for men with fertility concerns [1]

Some people who took retatrutide reported feeling nauseous or dealt with diarrhea, constipation or vomiting

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Interaction with Medications: Potential interactions with other drugs have not been systematically studied