The most commonly reported adverse effects of Wegovy include: Gastrointestinal symptoms : nausea, vomiting, diarrhoea, constipation, and abdominal discomfort Injection site reactions : redness, itching, or mild swelling at the injection site Fatigue or headache in some individuals These side effects are generally mild to moderate and tend to diminish as the body adjusts to the medication, particularly during the gradual dose-escalation schedule designed to improve tolerability
doi: 10.1007/s00404-015-3646-9
Additionally, IN delivery bypasses the gastrointestinal tract and hepatic first-pass metabolism, potentially leading to improved bioavailability of oral iron chelators like DFP (Pires et al., 2009
The temporal dynamics are fascinating
This is a winning option compared to the muscle loss and digestive distress that come along with GLP-1 injectables