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Despite extensive research, disease-modifying therapies remain elusive, hindered by late diagnosis, limited availability of specific biomarkers, and the persistent dominance of reductionist, single-target strategies

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The Trustees noted that as of 2024, an average beneficiarys Part B and D premiums plus cost sharing equated to about 26% of the average Social Security benefit , up from 7% in 1980 and 19% in 2000