Obvious reasons for excessive fatigue, such as anemia, can be ruled out on the CBC by screening for low RBC, altered hemoglobin, and abnormal RBC indices such as MCV, MCH, and MCHC
Thiols such as glutathione, alpha lipoic acid and N-acetyl-L-cysteine (NAC) are powerful sulfur-bearing antioxidants.*
L-glutathion is een tripeptide, opgebouwd uit de aminozuren glycine, cystene en glutaminezuur
5 l of hemolyzed blood was diluted in 1 ml of potassium phosphate buffer (0.05 M, pH 7.0) with EDTA 0.1 mM, and finally in 10 l of H 2 O 2 (1 M) according to the standard procedure of Beers and Sizer
Lambs 0.5mL at tailing or weaning Sheep 1mL pre-lambing Calves 2 - 3mL from 2 months of age Cows 4 - 6mL pre-calving Cobalt deficiency in soil and/or pasture leads to a lack of Vitamin B12 in body tissues of stock which, subsequently, may have poor growth rates and ill thrift, particularly in young animals Before treatment, establish pasture cobalt levels and/or Vitamin B12 status of stock Treatment is likely to last only 4-6 weeks if liver storage levels of Vitamin B12 and pasture levels of cobalt are low Treatment of pregnant ruminants should benefit newborn animals, particularly when treated in latter stages of pregnancy Supplementation of young ruminants should begin at or before weaning