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liraglutide: Head-to-head study reveals a diabetes risk difference Semaglutide and tirzepatide linked to fewer alcohol-related hospital visits Semaglutide dose may matter more than weight loss for heart health The overall incidence of medical encounters was included as an outcome for sensitivity analysis

The endothelium also generates a variety of vasodilators and vasoconstrictors, including thromboxane A2, endothelin, and Ang II (80)

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In addition to our included studies, there were more original studies excluded from our meta-analysis due to methodological differences and a lack of appropriate data, which provide additional support for GLP-1RAs role in reducing alcohol consumption