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Existing evidence indicates that FSP1 localizes to plasma membranes and lipid droplets, and its anti-ferroptotic properties are due to its association with plasma membranes and not with lipid droplets [44]

For in vitro-in vivo correlation, Clj m per kg body weight was calculated using the following measurements for Sprague-Dawley rats: 44.8 mg of protein per g of liver, 40 g of liver per kg of body weight

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Very few nutritional product manufacturers apply the same level of quality control or regulatory oversight to nutritional supplement manufacturing

Beyond the CRYOENDOMET clinical trial (NCT03627676), prospective, randomized, controlled, and well-powered trials with more extended follow-up are needed to assess optimal therapeutic management of AWE [21]