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Genetic mutations that inhibit MC4R signaling cause hyperphagia, decreased energy expenditure, and early-onset severe obesity, demonstrating the receptor's fundamental importance in weight regulation

Rodent behavioural paradigms (such as Morris water maze or novel object recognition) provide complementary in vivo endpoints for studying cognitive function-related signalling research questions.

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It captures them, neutralizes them, and ensures they are safely eliminated from the body

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