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An immune response to the oxidative metabolite of halothane can be induced in guinea pigs but no clinical toxicity was observed

Compelling findings from germ-free (GF) animal studies have demonstrated that the absence of microbiota leads to substantial neurodevelopmental abnormalities and altered behavior (Sudo et al., 2004

doi: 10.2337/dc14-1096

Symptoms worsen with sustained neck positions and improve with rest

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