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The glycine group lost 21% of body weight, reduced whole-body fat mass by 49%, and restored glucose tolerance, all while preserving more lean tissue than the control group

AOD9604 and Oral Bioavailability Research Pharmacokinetic profiling in pigs confirmed that AOD9604 is orally bioavailable, with intact peptide and its principal N-terminal truncation degradants (2aa and 3aa fragments) detected in plasma following oral dosing

Peptides are fragile molecules, and aggressive agitation can cause denaturation and aggregation, essentially damaging the protein structure

Bone turnover markers: In the elderly control group, OC decreased by 45% and CTX increased by 75%

The addition of lipoic acid further increased improvements in both clinical symptoms and NCV